Topics
toxicity testing
November 29, 2017
U.S. NAS workshop suggests comparing non-animal tests to human, not rodent, data, predicts alternatives to soon replace whole-animal tests; ECHA sees “long-way” until regulatory acceptance of alternatives for complex endpoints
Reading time: 2 minutes
November 17, 2017
Scientists highlight BPA’s interactions with multiple molecular targets besides estrogen receptor; growing body of evidence demonstrates similar pleiotropic actions of BPA substitutes such as BPS, BPF, BPAF and others
Reading time: 8 minutes
October 16, 2017
McGill University study shows exposure of pregnant rats to DINCH results in liver metabolism impairment and ‘testicular atrophy’ in the male progeny; BASF scientists depict study as ‘flawed,’ maintain that DINCH is safe for use in food contact applications
Reading time: 2 minutes
October 16, 2017
ANSES finds insufficient data to conclude on the potential endocrine disrupting properties of tetramethylbisphenol F (TMBPF), a bisphenol A alternative
Reading time: 2 minutes
October 10, 2017
Experts from academia, food industry and authorities present scientific and practical challenges in toxicological assessments and migration measurements
Reading time: 5 minutes
August 24, 2017
New scientific article reviews food contact chemicals’ effects on gut permeability, microbiota, and immune responses; scientific justification for risk assessment assumptions questioned
Reading time: 2 minutes
August 18, 2017
Scoping review identifies potential health effects of melamine other than renal damage, including impacts on neurological functions, behavior, reproduction, and growth
Reading time: 3 minutes
August 18, 2017
Scientists demonstrate utility of bioassays in FCM safety assessment using 4-nonylphenol (4NP) as model substance; 4NP levels detected by bioassays considered relevant for safety assessment
Reading time: 3 minutes
July 21, 2017
Scientists analyze estrogen- and androgen-like properties of BPA analogues using cell-based high throughput microscopy-employing tests; demonstrate anti-estrogenic and anti-androgenic properties of TMBPF
Reading time: 2 minutes
July 14, 2017
New scientific study by FPF summarizes research on alternative toxicity testing of FCMs, finds approach promising and feasible; sample preparation methods need to be optimized and standardized; employed assays should be of clear human health relevance
Reading time: 3 minutes
