On June 30, 2020, the Food Packaging Forum (FPF) will hold a webinar featuring a presentation from Alan Bergmann from the Swiss Centre for Applied Ecotoxicology on recent research developing novel bioassays to improve testing of food contact materials (FCMs); method improves sensitivity of detecting estrogenicity within complex mixtures of chemicals
EFSA: Public consultation on assessing chemical mixtures
EFSA releases draft guidance documents on risk and genotoxicity assessment of chemical mixtures; public consultations open until September 15 and September 9, 2018
Plastic use and exposure to estrogenic chemicals
U.S. pilot study asks participants to reduce plastic use related to food purchase, preparation, storage; blood samples indicate decrease in total estrogenic activity after changing plastic use behavior
ANSES: Not enough data on TMBPF
ANSES finds insufficient data to conclude on the potential endocrine disrupting properties of tetramethylbisphenol F (TMBPF), a bisphenol A alternative
High throughput in vitro testing of BPA analogues
Scientists analyze estrogen- and androgen-like properties of BPA analogues using cell-based high throughput microscopy-employing tests; demonstrate anti-estrogenic and anti-androgenic properties of TMBPF
DEHP increases BPA exposure
Scientists show that diethylhexyl phthalate (DEHP) leads to higher accumulation of bisphenol A (BPA) in reproductive tissues of mice, likely due to competition for detoxification enzymes
Estrogenic activity of BPA alternatives
Study assesses estrogenicity of bisphenol A and 6 bisphenol analogues in human breast cancer cell model; all bisphenols show estrogenic activity; 3 bisphenols more potent than BPA
Summary on estrogenic chemicals and reproductive health
PLOS Biology article highlights reproductive health impacts of estrogenic chemicals such as bisphenol A, its analogues, and phthalates
Epidemiology of mixtures: Xenoestrogens and breast cancer
Scientists find strong association between breast cancer risk and total burden of xenoestrogens; in contrast, individual compounds show only weak associations, if any
Court battle over estrogenicity of BPA-free plastic
Updated report on legal battle involving Tritan® plastic marketed as “EA-free”