Non-intentionally added substances (NIAS)

NIAS are chemicals present in food contact materials and articles which have not been added for a technical reason. They include side products, breakdown products, and contaminants. Although more and more NIAS have been identified over time, by far not all are known. Risk assessment and management of NIAS therefore present particular challenges. The updated dossiers in English and German replace the previous edition with the DOI: 10.5281/zenodo.33514.  

Researchers report NIAS migration from baby food pouches

Study performs migration testing on 79 plastic baby food pouches; finds four bisphenols, five phthalic acid diesters in targeted analysis and 26 more in suspect screening including 23 non-intentionally added substances (NIAS); NIAS adipic acid – diethylene glycol exceeds the threshold of toxicological concern in 40% of the pouches

Oligomer migration from PET and Tritan™

Scientists find cyclic polyethylene terephthalate (PET) oligomers migrate into fatty food simulants but not olive oil; levels higher from recycled compared to virgin PET; comprehensive extraction and migration experiments of Tritan™ products find oligomer migration from bottles of no toxicological concern but microwaveable containers were non-suitable for food heating

Analyzing NIAS in harmonized and non-harmonized FCMs

International Life Sciences Institute Europe publishes document on analytical methods and challenges in identifying non-intentionally added substances (NIAS); focus on non-harmonized food contact materials (FCMs) including silicones, inks, adhesives; discusses strengths and limitations of various methods; includes proposal on communication along the supply chain

Chemical characterization of post-consumer and recycled plastics

Scientists perform target and non-target screening of recycled plastics and provide recommendations on methods; detect >280 organic chemicals and metals in 21 plastic flakes and pellets used in recycling; analyze several recycled polymers and find polyethylene terephthalate (PET) the only one currently complying with European circular economy requirements; compare analytical methods to assess the chemical composition of recyclates giving their strenghts and limitations

Toward a guidance to assess safety of food packaging coatings

Interlaboratory study evaluates protocol for consistent safety assessment of coated metal packaging materials; guidance comprises sample preparation, chemical and biological analysis; finds technical differences affect outcome; emphasizes need for aligned protocol to avoid inconsistencies

Oligomers – presence in FCMs and food, toxicity, challenges

Review summarizes analysis and presence of oligomers in food contact materials (FCMs) made of polyethylene terephthalate (PET), polybutylene terephthalate (PBT), and polystyrene (PS) including challenges; study suggests ionic strength may influence migration of polyamide (PA) oligomers from PA FCMs

Study investigates quantity and risk of oligomers in PBT

Researchers analyze oligomer in extracts and migrates of polybutylene terephthalate (PBT) food contact articles also comparing levels in food and food simulants; report human exposure to oligomers can exceed daily threshold in some scenarios; express the need for toxicological evaluation of PBT oligomers

Researchers detect chemicals present in and migrating from PET bottles

Two studies analyze polyethylene terephthalate (PET) chemicals; identify several volatile chemicals present in and migrating from new PET bottles as well as from bottles commercially available in Japan; develop online method for quantifying non-intentionally added substances (NIAS)

Oligomers from plastic FCMs reviewed

The diversity of oligomeric migrants increases with new (co)monomer varieties used in plastic production; quantitative analysis and toxicological evaluation are challenging

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