A recent study explores the diversity of chemicals migrating from food contact articles into food simulants; 73% of extractable chemicals also migrated to food simulants; only 2% could be matched to currently known plastic chemicals; all migrates activated nuclear receptors, may disrupt metabolism or the endocrine system; migrates from PUR, PVC and LDPE contained more chemicals than other tested polymers and were more toxic
June 20, 2024
Chronic PS nanoplastics exposure found to impact mitochondrial health, impairing cell metabolism
New study examines long-term effects of polystyrene (PS) nanoplastics on mitochondrial health under realistic exposure conditions; repeated exposure to PS nanoplastics impaired mitochondrial function and cell differentiation process, possibly linked to metabolic disorders, such as diabetes and obesity; other recent studies found that PS micro- and nanoplastics negatively affect immune function, pregnancy outcomes, and gut health in various models
March 22, 2024
Majority of plastic food contact articles likely endocrine and metabolism disrupting
Two studies investigating chemicals from retail plastic food contact articles find considerable variability in complexity, with subsequent effects on cell-based tests of hormone disruption; many more chemicals measured from PVC and polyurethane than other polymers though the chemical mixtures from majority of the plastic samples are hormone disrupting; further evidence of PVC and PUR can interfere with GPCR-based cell communication
October 29, 2019
FPF Workshop 2019: Non-monotonicity explained
Ana Soto presents biological mechanisms underlying non-monotonic dose-responses, explains why non-monotonicity is ‘useful to organisms, challenging for regulators,’ discusses CLARITY-BPA’s successes and limitations
November 23, 2018
Meta-analysis of BPA’s link to diabetes
Meta-analysis of epidemiological studies finds positive association between BPA exposure and type 2 diabetes risk
August 15, 2018
Chemicals in plastics and obesity
U.S. researchers discuss contribution of exposure to endocrine disruptors to metabolic disorders such as obesity and diabetes
May 28, 2018
Can chemicals lead to weight gain?
Podcast highlights role of obesogenic chemicals in obesity epidemic with leading scientist in the field; other academics remain skeptical of impact of obesogens
March 13, 2018
Webinar on metabolic disruptors
Prof. Dr. Bruce Blumberg discusses chemicals that can interfere with the body’s fat metabolism in webinar hosted by Collaborative on Health and the Environment (CHE) on March 21, 2018
Topics: events, metabolic disruptor
February 16, 2018
Alternative plasticizers adipogenic in vitro
Several alternative plasticizers used in FCMs shown to promote lipid accumulation in vitro; direct activation of PPARγ suggested as possible mechanism
February 15, 2018
PFASs linked to weight gain
New study by Harvard scientists finds association between higher PFASs blood levels and greater weight gain after dieting; high PFASs levels also linked to low resting metabolic rates
