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mixture toxicity

October 17, 2023

Minderoo Foundation systematically maps human health effects from plastic-associated chemicals

Interactive and openly available, the Plastic Health Map summarizes human health outcomes of certain plastic-associated chemicals and particles as published by peer-review articles between 1960 and 2021; includes more than 3500 studies for 1557 chemicals; identifies gaps, including only 30% of chemicals have been investigated for health impacts, few studies in low-income countries
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Reading time: 4 minutes

August 21, 2023

Scientists recommend policy actions to reduce EDC health impacts

Review describes how cost and disease burden of endocrine-disrupting chemicals (EDCs) can be reduced by policy actions informed by science; recommended solutions include updating testing to account for mixture, cumulative exposure, effects occurring later life; second review summarizes studies linking EDC exposure with immunological and metabolic impacts during pregnancy
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Reading time: 3 minutes

November 24, 2022

Phthalates: impact on leiomyoma growth and mixture risk

Study identifies mono(2-ethyl-5-hydroxyhexyl) phthalate (MEHHP) exposure as high-risk factor for leiomyoma growth on epidemiological and mechanistic level; European biomonitoring of five reprotoxic phthalates demonstrates necessity to integrate mixture risk assessment into regulatory practice; targeted analysis shows migration of five phthalates from polypropylene food packaging
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Reading time: 7 minutes

October 26, 2022

Scientists present and apply spectral database on plastic additives

Researchers develop high-resolution spectral database and method for the identification of 56 selected organic plastic additives; indicates presence of multiple additives when applied to polypropylene and polylactic acid food packaging; highlight chemical signature not polymer but product dependent and “bioplastic” just as conventional plastics contain harmful additives
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Reading time: 4 minutes

January 24, 2022

Public consultation on REACH review

European Commission (EC) opens a public consultation period concerning the revision of REACH regulation; REACH is responsible for outlining chemical assessment procedures in the EU; possible updates include assessing chemical mixtures, simplifying safety data sheets, and incorporating essential-use concept; consultation period open until April 15, 2022
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Reading time: 1 minute
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