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in vitro

October 26, 2022

Scientists present and apply spectral database on plastic additives

Researchers develop high-resolution spectral database and method for the identification of 56 selected organic plastic additives; indicates presence of multiple additives when applied to polypropylene and polylactic acid food packaging; highlight chemical signature not polymer but product dependent and “bioplastic” just as conventional plastics contain harmful additives
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Reading time: 4 minutes

August 18, 2021

Toxicological and chemical profiling of plastic migrates

Scientific study investigates in vitro toxicity and composition of chemical mixtures migrating from everyday plastic products made of eight polymer types; demonstrates that thousands of chemicals can leach under realistic use conditions, including compounds toxic in vitro that contribute to human exposure; emphasizes the importance to rethink and redesign plastics to achieve safe materials
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Reading time: 3 minutes

December 15, 2020

Using ToxCast data to assess food chemicals

Scientists explore the utility of-throughput screening data for hazard assessment and toxicological read-across of food-relevant chemicals; observe some biological targets to lack validated toxicity associations; demonstrate application in identifying out-of-domain compounds
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Reading time: 3 minutes

October 8, 2020

Bioassays

Rapid and cost-effective non-animal-based in vitro bioassays can be used to improve the toxicological testing of food contact materials; journal article reviews currently available assays and future challenges
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Reading time: 2 minutes

August 23, 2019

Benchmarking in vitro toxicity of plastics

Scientists investigate in vitro toxicity and chemical composition of plastic consumer products made of different polymers; high baseline toxicity of polylactic acid (PLA) bioplastics; food contact status does not necessarily imply lower toxicity
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Reading time: 4 minutes
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