Topics
in vitro
September 21, 2018
11th BioDetectors conference addresses use of cell-based bioassays in food contact material safety analysis
Reading time: 4 minutes
September 7, 2018
Academic and industry scientists debate whether use of mechanistic data in regulatory hazard assessment of chemicals should be decisive or supportive only, discuss study selection process for systematic reviews
Reading time: 2 minutes
March 16, 2018
In vitro assays and alternative approaches being developed for EPA’s Endocrine Disruptor Screening Program and within EU-ToxRisk are hitting ground
Topics: in vitro, toxicity testing
Reading time: 2 minutes
March 9, 2018
U.S. EPA publishes draft strategy for use of alternative toxicity tests in evaluation of chemicals under updated chemicals regulation
Reading time: 1 minute
February 16, 2018
Several alternative plasticizers used in FCMs shown to promote lipid accumulation in vitro; direct activation of PPARγ suggested as possible mechanism
Reading time: 2 minutes
January 19, 2018
In vitro assays demonstrate significant biological activity in extracts from diverse food contact articles made of paper and board; bioassays expected to become accepted tool for assessment of FCM safety
Reading time: 1 minute
January 12, 2018
U.S. National Academy of Sciences’ report outlines research strategy to assess the need for chemical risk assessments to consider interactions between chemicals and microbiota when estimating human health effects
Reading time: 3 minutes
November 29, 2017
U.S. NAS workshop suggests comparing non-animal tests to human, not rodent, data, predicts alternatives to soon replace whole-animal tests; ECHA sees “long-way” until regulatory acceptance of alternatives for complex endpoints
Reading time: 2 minutes
August 18, 2017
Scientists demonstrate utility of bioassays in FCM safety assessment using 4-nonylphenol (4NP) as model substance; 4NP levels detected by bioassays considered relevant for safety assessment
Reading time: 3 minutes
June 2, 2017
Scientists test paper and board FCMs in 8 in vitro bioassays; all 20 samples showed positive responses in at least one of the assays; chemicals in paper and board FCMs require further investigation to ensure safety
Reading time: 5 minutes
