Chronic PS nanoplastics exposure found to impact mitochondrial health, impairing cell metabolism

New study examines long-term effects of polystyrene (PS) nanoplastics on mitochondrial health under realistic exposure conditions; repeated exposure to PS nanoplastics impaired mitochondrial function and cell differentiation process, possibly linked to metabolic disorders, such as diabetes and obesity; other recent studies found that PS micro- and nanoplastics negatively affect immune function, pregnancy outcomes, and gut health in various models

Immunomodulatory effects of EDCs

Scientists review studies reporting that some endocrine disrupting chemicals (EDCs) can affect development and functions of human immune cells; consequences include altered responses to infections and development of immune related diseases; food contact material (FCM)-relevant immunomodulatory EDCs include bisphenols, phthalates, triclosan

Immunotoxicity testing for FCM assessment

FDA scientists review currently available tools, discuss how they might be used for developmental immunotoxicity assessment of food contact materials