Topics
immunotoxicity
October 26, 2026
European Food Safety Authority (EFSA) publishes guidance for assessing safety of bisphenols and their derivatives used as replacements of bisphenol A (BPA) in food contact materials; extends these requirements to non-classified bisphenols and derivatives to help prevent regrettable substitution; specifies data requirements for different migration levels, including toxicokinetic properties and data on immunotoxicity, developmental, reproductive, and metabolic toxicity
Topics: bisphenols, BPA, EFSA, food safety, immunotoxicity, metabolic disruptor, reproductive health
Reading time: 3 minutes
June 20, 2024
New study examines long-term effects of polystyrene (PS) nanoplastics on mitochondrial health under realistic exposure conditions; repeated exposure to PS nanoplastics impaired mitochondrial function and cell differentiation process, possibly linked to metabolic disorders, such as diabetes and obesity; other recent studies found that PS micro- and nanoplastics negatively affect immune function, pregnancy outcomes, and gut health in various models
Reading time: 3 minutes
April 9, 2020
Scientists review studies reporting that some endocrine disrupting chemicals (EDCs) can affect development and functions of human immune cells; consequences include altered responses to infections and development of immune related diseases; food contact material (FCM)-relevant immunomodulatory EDCs include bisphenols, phthalates, triclosan
Reading time: 2 minutes
April 9, 2020
FDA scientists review currently available tools, discuss how they might be used for developmental immunotoxicity assessment of food contact materials
Reading time: 2 minutes
