Topics
toxicity testing
July 7, 2017
Scientists compile comprehensive review on phthalates, focus on human health effects observed in epidemiological and clinical studies
Reading time: 1 minute
June 9, 2017
Scientists compile inventory of compounds potentially used in coatings; 1,976 substances have no (recent) toxicological evaluation; subset analyzed by in silico tools and literature search, 10 compounds designated as 'high concern'
Reading time: 3 minutes
June 2, 2017
Scientists test paper and board FCMs in 8 in vitro bioassays; all 20 samples showed positive responses in at least one of the assays; chemicals in paper and board FCMs require further investigation to ensure safety
Reading time: 5 minutes
June 2, 2017
Scientists show that diethylhexyl phthalate (DEHP) leads to higher accumulation of bisphenol A (BPA) in reproductive tissues of mice, likely due to competition for detoxification enzymes
Topics: bisphenol A, estrogenic, mixture toxicity, parabens, phthalates, toxicity testing, triclosan
Reading time: 2 minutes
May 31, 2017
JRC expert survey identifies gaps in test methods for evaluating endocrine disruptors; new methods for thyroid, metabolic, immune disorders, as well as hormone-related cancers seen as priority
Reading time: 1 minute
May 26, 2017
U.S. federal agencies' committee releases draft roadmap for further developmnt of alternative testing approaches, aimed at improving regulatory acceptance; public consultation open until August 31, 2017
Topics: regulation, toxicity testing
Reading time: 1 minute
May 16, 2017
Scientists review studies on the use of select bioassays to assess hazard of food contact materials; bioassays considered a useful addition to targeted chemical analysis, especially in the assessment of finished materials and articles
Topics: migration, toxicity testing
Reading time: 1 minute
May 12, 2017
CLARITY-BPA study finds BPA exposure to increase incidence and severity of cardiomyopathy, promoting myocardial degeneration; BPA’s cardiotoxicity could be caused by adverse vascular events
Reading time: 1 minute
March 24, 2017
OECD publishes guidance on the use of Adverse Outcome Pathways (AOPs) in developing Integrated Approaches to Testing and Assessment (IATA); AOPs to support chemical grouping, development of models, test methods, and testing strategies, and interpretation of test results
Reading time: 2 minutes
March 17, 2017
Integrative Environmental Medicine book provides comprehensive overview of chemical effects on health, outlines resources and tools helping to reduce exposure and risks
Reading time: 1 minute