Topics
toxicity testing
February 10, 2017
Review article by EU Commission’s Joint Research Centre and collaborators discusses development and use of computational prediction models for regulatory toxicology and how it can be supported by the Adverse Outcome Pathways framework
Topics: toxicity testing
Reading time: 3 minutes
February 10, 2017
Scientists propose strategy for prioritizing assessment of non-evaluated chemicals potentially present in printed paper and board FCMs with help of quantitative structure-activity relationship (QSAR) models; identify 106 substances of highest concern
Topics: paper & board, toxicity testing
Reading time: 4 minutes
February 9, 2017
Swedish Chemicals Agency publishes report on the replacement, reduction and refinement of animal experiments to assess chemical safety
Topics: risk assessment, toxicity testing
Reading time: 1 minute
February 7, 2017
New OECD document discusses the use of alternative testing strategies in risk assessment of nanomaterials; makes recommendations to advance the field within coming years
Topics: nanomaterials, toxicity testing
Reading time: 2 minutes
January 25, 2017
Oral ingestion of titanium dioxide nanoparticles induces abnormal immune responses, preneoplastic lesions in the colon; scientists call for re-evaluation of risks from oral exposure to nanoparticles
Reading time: 3 minutes
December 23, 2016
Scientists review migration of nanomaterials from polymer-based FCMs, question suitability of migration testing conditions and diffusion-based models for estimation of nanomaterials migration, point to knowledge gaps regarding actions in human body
Reading time: 5 minutes
December 23, 2016
Exposure of pregnant and lactating mice to human-exposure-relevant dose of bisphenol S (BPS) impairs maternal behavior, what can lead to lower offspring survival; behavioral effects also seen in daughters of exposed mice
Reading time: 2 minutes
December 20, 2016
EFSA publishes official report from the June 2016 colloquium on epigenetics in risk assessment
Reading time: 1 minute
December 2, 2016
Videos of presentations and panel discussions held at ILSI North America workshop on safety evaluation of FCMs in September 2016 are now available online
Reading time: 1 minute
November 16, 2016
European Union Reference Laboratory for Alternatives to Animal Testing (EURL ECVAM) publishes 2016 status report providing an update on its activities
Topics: JRC, toxicity testing
Reading time: 1 minute
