Scientific study evaluates presence of hazardous chemicals in methanolic extracts from paper and cardboard food contact materials (FCMs) using several bioassays; finds oxidative stress (52%), genotoxicity (100%), impacts on xenobiotic metabolism (74%), antiandrogenic (52%) and antioestrogenic effects (39%); recommends an effect-based approach for hazard identification of food contact chemicals
EDQM guide on European paper and board FCM regulations
The European Directorate for the Quality of Medicines and Healthcare (EDQM) publishes “technical guidance relating to the requirements, compliance testing and supporting documentation for paper and board materials” used in food contact materials and articles; includes overview of European FCM regulations, aims to harmonize paper and board regulation; provides instructions to test compliance, detect recycled materials, prepare supporting documentation