US Food and Drug Administration (FDA) proposes structural changes within the institution in response to recent critique; includes increased focus on nutrition, partnerships with other regulatory authorities and incorporating outside advisors; Center for Science in the Public Interest (CSPI) publishes report on obesogens; encourages FDA to ‘incorporate framework’ to identify obesogens and other endocrine disruptors when reviewing chemical safety
BPA substitutes and chromosomal abnormalities
Mice exposed to low doses of BPA, BPS, diphenyl sulfone, BPF, BPAF exhibit chromosomal abnormalities that persist for several generations, according to new study in Current Biology
EDCs impact neurodevelopment across generations
Scientists obtain epidemiological evidence demonstrating adverse effects of EDC exposure on neurodevelopment in humans across several generations
Epigenesis in response to stress and toxicants
Adverse environmental influences during childhood act through epigenetic mechanisms to increase disease rates in adults; trigger factors include stress and childhood trauma, malnourishment, exposure to toxicants
DEHP and male reproductive health
New research finds reproductive abnormalities in male mice prenatally exposed to DEHP and their succeeding generations; 3rd generation effects most pronounced at lowest exposure dose
Epigenetics in risk assessment
Current state of epigenetics science and potential integration of epigenetic effects into risk assessment discussed at EFSA colloquium
Colloquium on epigenetics and risk assessment
EFSA hosts scientific colloquium on epigenetics and risk assessment on June 14-15, 2016 in Valencia; registration open until April 27, 2016
EFSA: three video sessions of 2nd scientific conference published
Highlights of the sessions on epigenetics, weighing evidence, and environmental risk assessment summarized