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Canada proposes grouping BPA analogues, alternatives

Environment and Climate Change Canada (ECCC) and Health Canada (HC) propose grouping 343 bisphenol A (BPA) structural analogues and functional alternatives under Chemicals Management Plan; request feedback on selection method and grouping until February 17, 2021

On January 13, 2021, news provider Chemical Watch reported on a technical consultation launched by Environment and Climate Change Canada (ECCC) and Health Canada (HC). The agencies propose the grouping of 343 chemicals related to bisphenol A (BPA CAS 80-05-7) under its Chemicals Management Plan (CMP).

Regulatory action on bisphenol A (BPA), and a shift towards BPA-free products, have led to increased use of alternatives, such as bisphenol S (BPS CAS 80-09-1) (FPF reported). However, these substitutes are often structurally very similar to BPA, which has been linked to a range of human health and environmental impacts including endocrine disruption (FPF reported).

According to the authors of the consultation document, there is an “ongoing need to consider the broader group of bisphenols.” The 343 substances were selected based on their structural and functional similarity and separated into 23 subgroups using tools such as the OECD’s QSAR toolbox.

The technical consultation is now seeking public comments on, among others, the methods used to identify the broader group of BPA analogs and functional alternatives as well as the proposed sub-grouping of substances.

Publication of the technical consultation document represents the first step in developing a problem formulation for structural analogs and functional alternatives for BPA. The public consultation is open until February 17, 2020.

Read More

Government of Canada (December 2020). “Technical consultation: proposed subgrouping of bisphenol A (BPA) structural analogues and functional alternatives.

Emma Davies (January 13, 2020). “Canada consults on grouping of 343 BPA analogues and alternatives.” Chemical Watch

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