Review describes how cost and disease burden of endocrine-disrupting chemicals (EDCs) can be reduced by policy actions informed by science; recommended solutions include updating testing to account for mixture, cumulative exposure, effects occurring later life; second review summarizes studies linking EDC exposure with immunological and metabolic impacts during pregnancy
Researchers detect microplastics in human semen and heart
Four recent studies assess microplastics: in human semen, heart, from baby food containers, and suitability of in vitro models to investigate human health effects; find microplastics in six out of ten semen samples, find impacts on semen quality; samples from cardiac surgery patients contain microplastics in heart and surrounding tissue; billions of nano- and microplastics released from plastic baby food containers; outline challenges and recommendation of studying plastic particles in vitro
Degradation of compostable plastics can increase toxicity, scientists emphasize
Studies analyze biodegradable – including compostable – plastics for their in vitro toxicity and chemical composition; comparison with conventional plastics indicates higher toxicity of compostables which further increases with photodegradation and composting; detect brominated flame retardants in “biodegradable”-labeled food packaging
Scientists find most silicon rubber kitchenwares are endocrine disrupting
Study determines toxicity and composition of 42 silicon rubber food contact articles; finds 84% of silicon kitchenware to induce endocrine activity; review gives update on the known endocrine disruptors phthalates and bisphenols with focus on detection methods and addressing regulatory concerns; study develops and applies method for phthalate determination in vegetable oils
Toward a guidance to assess safety of food packaging coatings
Interlaboratory study evaluates protocol for consistent safety assessment of coated metal packaging materials; guidance comprises sample preparation, chemical and biological analysis; finds technical differences affect outcome; emphasizes need for aligned protocol to avoid inconsistencies
Biodegradable plastics may bring degradation and toxicity challenges, say scientists
In an opinion piece published in Waste Management scientists emphasize there is no universal biodegradability of plastics in any ecosystem; waste collection systems need adaptation and toxicity testing improvements; experimental study finds leachates of biodegradable plastic items affect mussel early embryo stages development and adult physiological parameters
Microplastics impacts on the reproductive system and offspring
Scientists report human-relevant polystyrene (PS) microplastic concentrations change mice placental metabolism; show nanoplastics have variable effects on placental enzymes using simulations; find pre- and postnatal PS microplastic exposure affects male mice testis development and fertility; recommend future research to analyze multigenerational effects
Study investigates quantity and risk of oligomers in PBT
Researchers analyze oligomer in extracts and migrates of polybutylene terephthalate (PBT) food contact articles also comparing levels in food and food simulants; report human exposure to oligomers can exceed daily threshold in some scenarios; express the need for toxicological evaluation of PBT oligomers
Chemicals used to produce PET cause cells to store fat, say scientists
Study investigate correlation of starting substances to manufacture polyethylene terephthalate (PET) with obesity; report these para-phthalates to alter adipogenesis in vitro at nanomolar concentrations; consider ascertaining their safe levels a high priority
Microplastics in humans: current knowledge and potential implications
Review summarizes microplastics abundance and characteristics in human biological samples including current research approaches employed, challenges, and prospects; study indicates microplastics impact human meconium and placenta microbiota; review outlines current evidence on microplastic effects upon exposure during early developmental stage