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toxicity testing

October 9, 2023

Scientists detect microplastics in amniotic fluid, effects on testicular aging

Two studies investigate microplastic presence or effects in female and male reproductive organs; small cohort study finds low number of microplastics to be present in human amniotic fluid besides the placenta; in vitro and mice in vivo study reports microplastics induce premature testicular aging and identifies underlying pathways
Reading time: 3 minutes

September 26, 2023

A novel concept for improved safety assessment of FCMs guided by public health concerns

Over 20 scientists present a vision for safer food contact materials (FCMs); propose new approach to test all chemicals that migrate from final product for their contribution to highly prevalent chronic diseases
Reading time: 3 minutes

September 21, 2023

More research on oligomers needed, scientists say

Perspective article emphasizes that the “invisible” part of polymers, the oligomers, have been overlooked with the focus being on the “visible” part, the microplastics; urgency to increase knowledge on oligomer properties, environmental behavior, and toxicity given their ever-increasing diversity, quantity, and potential toxicity
Reading time: 2 minutes

August 31, 2023

Microplastics can lead to behavioral changes in mice

Scientists find polystyrene microplastics reduce cell viability, translocate in the body, modify mice behavior, and change their liver and brain immune markers after short-term exposure; effects potentially age-dependent; two reviews summarize nano- and microplastic impacts on fertility and potential implications
Reading time: 3 minutes

August 30, 2023

Summer 2023 research snapshot: PFAS in food packaging, food, and potential health impacts

A summary of eight studies; scientists quantify per- and polyfluoroalkyl substances (PFAS) in French fast food packaging; detect eleven PFAS in baking trays from China but not Spain; find PFAS in straws made of paper, bamboo, glass, and plastic; “compostable” service ware can contaminate compost with PFAS; find PFAS in edible oil worldwide; further articles focus on PFAS in drinking water, in Asia, and effects on child respiratory health
Reading time: 10 minutes

August 21, 2023

Scientists recommend policy actions to reduce EDC health impacts

Review describes how cost and disease burden of endocrine-disrupting chemicals (EDCs) can be reduced by policy actions informed by science; recommended solutions include updating testing to account for mixture, cumulative exposure, effects occurring later life; second review summarizes studies linking EDC exposure with immunological and metabolic impacts during pregnancy
Reading time: 3 minutes

August 7, 2023

Researchers detect microplastics in human semen and heart

Four recent studies assess microplastics: in human semen, heart, from baby food containers, and suitability of in vitro models to investigate human health effects; find microplastics in six out of ten semen samples, find impacts on semen quality; samples from cardiac surgery patients contain microplastics in heart and surrounding tissue; billions of nano- and microplastics released from plastic baby food containers; outline challenges and recommendation of studying plastic particles in vitro
Reading time: 5 minutes

August 4, 2023

Degradation of compostable plastics can increase toxicity, scientists emphasize

Studies analyze biodegradable – including compostable – plastics for their in vitro toxicity and chemical composition; comparison with conventional plastics indicates higher toxicity of compostables which further increases with photodegradation and composting; detect brominated flame retardants in “biodegradable”-labeled food packaging
Reading time: 3 minutes

March 7, 2023

Scientists find most silicon rubber kitchenwares are endocrine disrupting

Study determines toxicity and composition of 42 silicon rubber food contact articles; finds 84% of silicon kitchenware to induce endocrine activity; review gives update on the known endocrine disruptors phthalates and bisphenols with focus on detection methods and addressing regulatory concerns; study develops and applies method for phthalate determination in vegetable oils
Reading time: 4 minutes

February 27, 2023

Toward a guidance to assess safety of food packaging coatings

Interlaboratory study evaluates protocol for consistent safety assessment of coated metal packaging materials; guidance comprises sample preparation, chemical and biological analysis; finds technical differences affect outcome; emphasizes need for aligned protocol to avoid inconsistencies
Reading time: 2 minutes
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