Topics
modeling
November 14, 2024
VERMEER FCM tool allows modeling migration of organic chemicals from plastic food contact materials (FCMs), predicting selected toxicological endpoints, and comparing with European regulatory information; based on several in silico models; designed to assist risk assessment of FCMs; openly available
Reading time: 2 minutes
July 23, 2024
Study proposes a preliminary physiologically-based toxicokinetic (PBTK) model for micro- and nanoplastics (MNPs); polymer type, size, shape, surface chemistry, surface biofilms, and biocorona determine toxicokinetic rates; models for engineered nanoparticles are not appropriate due to heterogeneity of MNPs; uptake via inhalation and effects of absorbed chemicals need more investigation
Reading time: 3 minutes
July 17, 2023
Scientists develop nonlinear model for predicting food contact chemical (FCC) migration and apply it to FCCs of high toxicological concern; emphasize usefulness of their model to speed up migration assessment of FCCs; different group of scientists proposes an innovative modeling approach to assess release of a specific additives and elements from plastic food packaging and steel processing tools
Reading time: 4 minutes
June 10, 2022
Scientists evaluate global performance of new model to predict a chemical’s concentration in food in contact with food packaging; integrated model includes uncertainty analysis and can be used for regulatory purposes
Reading time: 2 minutes
February 10, 2021
Study in Environmental Science Technology on adapted General Unified Threshold model for Survival (GUTS) for environmental risk assessment of chemical mixtures; includes time dimension, approach can be extended to multiple compounds, evaluate synergistic or additive interaction
Reading time: 2 minutes
May 20, 2020
American Society for Cellular and Computational Toxicology (ASCCT) to hold webinar on May 26, 2020, discussing three recently completed projects developing collaborative in silico toxicology models
Topics: modeling, toxicity testing
Reading time: 1 minute
December 20, 2018
Food Packaging & Health article introduces concept of mathematical migration modeling, discusses approaches for different packaging materials, highlights benefits, limitations, research needs
Reading time: 1 minute
December 11, 2018
Technical University of Denmark contributes to 2 new Horizon 2020 research projects focused on endocrine disruptors, reproductive health, thyroid hormones; to begin in 2019 and run for 5 years
Reading time: 1 minute
October 9, 2018
Presentations at Food Packaging Forum 2018 workshop cover predictive toxicology, computational methodologies, green chemistry
Reading time: 3 minutes
June 29, 2018
FDA holds public hearing on its predictive toxicology roadmap, September 12, 2018; registration open until August 29, 2018; comments accepted after hearing until October 12, 2018
Reading time: 1 minute
