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June 28, 2024

European Chemicals Agency (ECHA) report outlines four key challenge areas concerning chemicals regulation in the EU; discusses protection against most harmful chemicals, particularly those inducing neurotoxicity, immunotoxicity, endocrine disruption; underscores the need for data transparency and a “lack of comprehensive information on many substances”, particularly polymers
Reading time: 2 minutes

June 27, 2024

Recent studies explore the presence and migration of diverse synthetic antioxidants in Chinese food contact materials (FCMs); both phosphite antioxidants and synthetic phenolic antioxidants are commonly found; typically, FCMs contain several mg of synthetic antioxidants per kg FCM and may be the primary source of exposure to synthetic antioxidants; some commonly found antioxidants are suspected endocrine disruptors
Reading time: 4 minutes

June 24, 2024

A recent study explores the diversity of chemicals migrating from food contact articles into food simulants; 73% of extractable chemicals also migrated to food simulants; only 2% could be matched to currently known plastic chemicals; all migrates activated nuclear receptors, may disrupt metabolism or the endocrine system; migrates from PUR, PVC and LDPE contained more chemicals than other tested polymers and were more toxic
Reading time: 3 minutes

June 20, 2024

New study examines long-term effects of polystyrene (PS) nanoplastics on mitochondrial health under realistic exposure conditions; repeated exposure to PS nanoplastics impaired mitochondrial function and cell differentiation process, possibly linked to metabolic disorders, such as diabetes and obesity; other recent studies found that PS micro- and nanoplastics negatively affect immune function, pregnancy outcomes, and gut health in various models
Reading time: 3 minutes

June 17, 2024

Study of colon cancer cell lines finds polystyrene micro and nanoplastic particles (MNPs) can be absorbed into cancerous cells in experimental settings; the more aggressive cell line absorbed the most MNPs and presence of MNPs increased cell movement; evidence of persistence and bioaccumulation; authors argue MNPs fit criteria as substance of concern under REACH
Reading time: 3 minutes
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