On September 28, 2018, the U.S. National Toxicology Program (NTP) updated its website on the CLARITY-BPA Program with a final version of the CLARITY-BPA core study research report (FPF reported) and a page providing access to the publications and primary data from the CLARITY-BPA grantee studies, i.e., studies performed by academic research institutions (FPF reported). Instead of the disputed conclusion that BPA caused “minimal effects” (FPF reported), the final version of the core study report now states that the effects were “sometimes occurring in only one low- or intermediate-dose group.” This pattern could be indicative of nonmonotonic responses (FPF reported).
NTP also confirmed that “a report integrating findings from the Core Study and Grantee Studies is expected in fall 2019” (FPF reported).
In an article published on September 28, 2018, the industry association American Chemistry Council (ACC) informed about the publication of the final core study report while not mentioning the academic studies or the integrative report yet to be released.
Read more
U.S. NTP (2018). “CLARITY-BPA Program.”
U.S. NTP (2018). “CLARITY-BPA. Study Data.”
ACC (September 28, 2018). “U.S. National Toxicology Program releases final report on CLARITY core study, again confirms BPA safety.”
Emma Davies (October 4, 2018). “CLARITY-BPA report steers clear of ‘minimal effects’ wording.” Chemical Watch
Heather Patisaul (October 10, 2018). “FDA far from achieving clarity on BPA.” Chemical Watch
Reference
U.S. NTP (September 2018). “NTP Research Report on the CLARITY-BPA Core Study: A perinatal and chronic extended-dose-range study of Bisphenol A in rats.”
