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Safety of DEHCH

EFSA assesses safety of bis(2-ethylhexyl)cyclohexane-1,4-dicarboxylate (DEHCH) for use as plasticizer in PVC; concluded to present no safety concerns; uncertainty remains about bioaccumulation potential in humans

On January 29, 2020, the European Food Safety Authority’s (EFSA) Panel on Food Contact Materials, Enzymes and Processing Aids published an assessment of the plastic additive bis(2-ethylhexyl)cyclohexane-1,4-dicarboxylate (DEHCH, CAS 84731-70-4) for use in food contact materials (FCMs). Specifically, DEHCH “is intended to be used as plasticizer in poly(vinyl chloride) (PVC) film [at] up to 25% w/w in contact with aqueous, acidic and low-alcohol foods for long-term storage at room temperature or below (refrigerated and frozen). The films are not intended for use in reheating food.”

The substance was found to “not raise a concern for genotoxicity.” In repeated dose toxicity studies, “no adverse effects were observed up to the highest tested dose of 1000 mg/kg body weight (bw) per day.” However, there remained some “uncertainty on the potential for accumulation for humans.” Nonetheless, the Panel “concluded that . . . [DEHCH] is not of safety concern for the consumer” when used under the intended conditions. A specific migration limit for the substance was set at 0.050 mg/kg food.

Read more

EFSA (2020). “Safety assessment of the substance bis(2-ethylhexyl)cyclohexane-1,4-dicarboxylate, for use in food contact materials.EFSA Journal 18: e05973.

Chemical Watch (February 4, 2020). “DEHCH safe for use in food packaging – Efsa.”

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