Topics
toxicity testing
October 26, 2016
European Food Safety Authority calls for stakeholder contributions to shaping its new project MixTox aiming to develop a harmonized methodology for risk assessment of chemical mixtures
Reading time: 1 minute
October 17, 2016
OECD endorses five new Adverse Outcome Pathways; cover liver fibrosis, heritable mutations, reproductive dysfunction, impairment of learning and memory abilities in children and adults; new background article on AOPs available on FPF website
Topics: risk assessment, toxicity testing
Reading time: 2 minutes
October 17, 2016
Adverse outcome pathway (AOP) describes the sequence of events linking initial molecular perturbations to adverse outcomes in organisms and populations; this framework supports the use of high-throughput animal-free toxicity testing methods in regulatory decision-making
Topics: risk assessment, toxicity testing
Reading time: 9 minutes
October 7, 2016
Scientists evaluate health effects of a mixture of 27 environmental chemicals in rats exposed to low concentrations comparable to current human exposure levels; find effects on weight, histology, gene expression in the liver, and metabolome of blood plasma
Reading time: 2 minutes
September 20, 2016
German Institute for Risk Assessment (BfR) summarizes its research on health and environmental safety of nanomaterials and other novel materials; nanoparticle detection optimized in different matrices; animal-free toxicity testing implemented
Reading time: 1 minute
September 16, 2016
Scientists test 65 chemicals migrating from ‘BPA-free’ baby bottles in a panel of in vitro assays for effects on seven receptors; 12 chemicals show no activity, 53 activate or inhibit at least one of the tested receptors
Reading time: 3 minutes
August 19, 2016
Scientists summarize the knowledge on the combined contribution of low-dose chemical exposures to carcinogenesis, identify research gaps, recommend novel methodologies for research and risk assessment
Reading time: 2 minutes
August 18, 2016
Nature commentary discusses three approaches towards safer chemicals and products: Standardized chemical safety tests, testing finished products, and publicly disclosing test results
Reading time: 2 minutes
August 12, 2016
Scientists evaluate a panel of novel plasticizers for in vitro effects on testicular function; propose alternatives to phthalates
Reading time: 2 minutes
August 10, 2016
New study shows that BPA and substitute BPS disrupt reproduction of roundworms causing germline apoptosis and embryonic lethality
Reading time: 1 minute
