Scientific review shows that some chemicals are proportionately more toxic at lower exposure levels; “dose makes poison” principle indicates that current risk assessment approaches underestimate chemical toxicity
Evidence on BPA’s ubiquity and low-dose effects
New study reviews and substantiates ubiquitous occurrence of bisphenol A in the environment and adverse health effects from low-dose exposures to it
Extranuclear actions of EDCs at low doses
Scientists review molecular mechanisms underlying low-dose actions of estrogenic EDCs, focusing on extranuclear signaling; BPA effects in pancreas and heart mediated through alpha, beta, and membrane-associated forms of estrogen receptor
Are ‘safe levels’ safe?
Article questions effectiveness of current chemical risk assessment in protecting public health; explains non-monotonic dose response and why it should be considered in assessing chemicals’ toxicity
EFSA: Non-monotonic dose response update
EFSA-commissioned review of non-monotonic dose response (NMDR) studies published; four substances relevant to food safety identified with potential for NMDR effects
Manmade vs. natural estrogens
Article in Nature Reviews highlights different effect potential of manmade vs. natural estrogens in the case of soy and bisphenol A in a study with women undergoing in vitro fertilization
Opinions: Toxic chemicals in everyday products
Article in New York Times outlines the issue of exposure to toxic chemicals from common products and the consequences for human health
2nd Scientific Statement on EDCs released
Endocrine Society summarizes EDC research of the past six years and links EDC exposure to various health problems
Endocrine Society: 2nd Scientific Statement on EDCs
Endocrine Society releases executive summary of second Scientific Statement on EDCs; mounting evidence on associations between exposure to EDCs and various health problems such as diabetes and obesity
EFSA’s work on endocrine disrupters is ongoing
EFSA gives update on their work on endocrine active substances and non-monotonic dose response; following up their Scientific Opinion of 2013