Topics
non-monotonic dose-response
December 20, 2017
Scientific review shows that some chemicals are proportionately more toxic at lower exposure levels; “dose makes poison” principle indicates that current risk assessment approaches underestimate chemical toxicity
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August 8, 2017
New study reviews and substantiates ubiquitous occurrence of bisphenol A in the environment and adverse health effects from low-dose exposures to it
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February 10, 2017
Scientists review molecular mechanisms underlying low-dose actions of estrogenic EDCs, focusing on extranuclear signaling; BPA effects in pancreas and heart mediated through alpha, beta, and membrane-associated forms of estrogen receptor
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June 29, 2016
Article questions effectiveness of current chemical risk assessment in protecting public health; explains non-monotonic dose response and why it should be considered in assessing chemicals’ toxicity
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May 4, 2016
EFSA-commissioned review of non-monotonic dose response (NMDR) studies published; four substances relevant to food safety identified with potential for NMDR effects
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March 30, 2016
Article in Nature Reviews highlights different effect potential of manmade vs. natural estrogens in the case of soy and bisphenol A in a study with women undergoing in vitro fertilization
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December 1, 2015
Article in New York Times outlines the issue of exposure to toxic chemicals from common products and the consequences for human health
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November 9, 2015
Endocrine Society summarizes EDC research of the past six years and links EDC exposure to various health problems
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September 29, 2015
Endocrine Society releases executive summary of second Scientific Statement on EDCs; mounting evidence on associations between exposure to EDCs and various health problems such as diabetes and obesity
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May 26, 2015
EFSA gives update on their work on endocrine active substances and non-monotonic dose response; following up their Scientific Opinion of 2013
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