Multistakeholder study presents framework to evaluate new approach methodologies for assessing safety of chemicals; uses three steps and set of core principles, criteria to check if fit-for-purpose; provides case studies illustrating application
Focus on EDC controversy
Health & Environment article outlines debate around 2012 WHO/UNEP report on EDCs; discusses value of state-of-the-science reviews and need for systematic review methods in complex research problems
How to group PFAS? Expert panel finds no single answer
Panel of 12 experts in the fields of per- and polyfluoroalkyl substances (PFAS) chemistry and toxicology, general mixtures risk assessment and toxicokinetics participate in series of blind surveys; experts representing academia, regulators, and consultants; discuss how to group PFAS
DEHP disrupts insulin signaling
Scientists find that long-term oral exposure of adult rats to the phthalate DEHP disrupts insulin signaling pathways, resulting in the development of insulin resistance
BPA linked to adverse effects in monkeys
New study confirms adverse effects of BPA in primates; finds oral bolus exposure inappropriate human exposure model
Antiandrogenic chemicals in food
Scientists review food components and contaminants that can act as (anti)androgens; in vitro-based computational model for interactions with androgen receptor identifies active chemicals in ToxCast dataset
CLARITY-BPA webinars: Key messages
Carnegie Mellon University and FDA hold webinars on CLARITY-BPA academic research and guideline studies; FDA upholds importance of high-dose effects; academic researchers highlight significant low-dose effects
NAMPA questions study linking BPA with autism
North American Metal Packaging Association responds to study linking BPA with autism: “study was of poor design with no control over contamination”
Glass industry launches sustainability label
European Container Glass Federation (FEVE) announces the launch of a new symbol for recycling on glass packaging; describes it as highlighting the brands’ commitments towards sustainability and health; to be promoted for use on all glass packaging applications including food and beverage, pharma, perfumery, cosmetic products
Researches develop and evaluate methods for food contact chemical determination
Propose method to analyze chemical markers of mineral oil aromatic hydrocarbons (MOAH) from printing inks in food packaging; present workflow that includes in silico prediction tools to identify nonvolatile migrates from food packaging; evaluate efficiency and reliability of methodology for non-target identification of volatile substances