Clinical study investigates 10 microplastic types in human placenta and meconium; detects polyethylene, polypropylene, polystyrene, and polyurethane in the samples; highlights that evaluation and control of potential contamination is crucial
FDA accused of ‘willful ignorance’ regarding BPA
U.S. NGO Environmental Health News criticizes FDA’s approaches to designing and performing CLARITY-BPA study, interpreting its results; presents results of own investigation suggesting intentional manipulation, potential industry influence
Nanomaterials regulation in different countries
New JRC-study reviews regulatory measures for nanotechnology in food and feed production in different countries; only EU and Switzerland have legally binding nano-specific provisions
Evaluation framework for new approach methodologies
Multistakeholder study presents framework to evaluate new approach methodologies for assessing safety of chemicals; uses three steps and set of core principles, criteria to check if fit-for-purpose; provides case studies illustrating application
Focus on EDC controversy
Health & Environment article outlines debate around 2012 WHO/UNEP report on EDCs; discusses value of state-of-the-science reviews and need for systematic review methods in complex research problems
How to group PFAS? Expert panel finds no single answer
Panel of 12 experts in the fields of per- and polyfluoroalkyl substances (PFAS) chemistry and toxicology, general mixtures risk assessment and toxicokinetics participate in series of blind surveys; experts representing academia, regulators, and consultants; discuss how to group PFAS
DEHP disrupts insulin signaling
Scientists find that long-term oral exposure of adult rats to the phthalate DEHP disrupts insulin signaling pathways, resulting in the development of insulin resistance
BPA linked to adverse effects in monkeys
New study confirms adverse effects of BPA in primates; finds oral bolus exposure inappropriate human exposure model
Antiandrogenic chemicals in food
Scientists review food components and contaminants that can act as (anti)androgens; in vitro-based computational model for interactions with androgen receptor identifies active chemicals in ToxCast dataset
CLARITY-BPA webinars: Key messages
Carnegie Mellon University and FDA hold webinars on CLARITY-BPA academic research and guideline studies; FDA upholds importance of high-dose effects; academic researchers highlight significant low-dose effects