Predictions of acute health hazards by ‘data fusion’ read-across structure activity relationship (RASAR) modeling reported to be more reproducible than animal testing data
Migration vs. solubility
New scientific study finds that in certain cases migration studies can be substituted by solubility measurements; modified OECD method shows solubility of select antioxidants, UV stabilizers in some food simulants is below SMLs
Studies assess PFAS, OPEs, and plasticizers in paper & board
Review summarizes per- and polyfluoroalkyl substances (PFAS) migration from paper food packaging into food and food simulants and identifies dietary exposure of PFAS as potential human health risk; study highlights need to further evaluate organophosphate esters (OPEs) and prohibited PFAS in paper and aluminum foil food packaging; scientists analyze and recommend extraction method to assess plasticizers in recycled paperboard
Prioritization of NIAS for risk assessment
Scientists propose strategy to prioritize non-intentionally added substances detected by non-targeted screening in paperboard FCMs for risk assessment based on exposure estimates and in silico predictions of toxicity
Plastic recycling: company commitments and chemical safety challenges
Scientists report most large companies commit to reducing plastic pollution but focus on recycling; extrusion of recycled materials and legacy compounds in recycled materials as safety challenge; some substances increase others decrease with the increase in recycled content in polyethylene terephthalate (PET) bottles; tentatively identify 212 volatile chemicals in 57 different recycled PET flakes available in China; present migration model to characterize the exposure and risk of PET oligomers
Chemical migration into coffee, canned vegetables, and Indian curd
Three research studies investigate the occurrence of chemicals in food packaging and migration into food; find average of 330 µg oligoesters migrating from cans per kg drained vegetables; report most extractable chemicals from low-density polyethylene Dahi curd packaging not included in India’s positive list; detect low levels of phthalic acid esters in coffee obtained from single-use capsules
Opinion: EDC criteria and potency
Scientists for Scientific European Commission Regulation publish opinion on the European Commission’s criteria for endocrine disrupting chemicals (EDCs); call for potency to be an aspect of regulatory EDC identification in line with industry views but not supported by the Endocrine Society
Hazard- vs. risk-based chemicals management
Hazard-based approaches are criticized and risk-based management of chemicals is pushed for in Europe; doing so would weaken the protection of public health, International Chemical Secretariat (ChemSec) explains
Beyond BPA – Many bisphenols migrate from food packaging
Four studies investigate bisphenol (BP) migration from food packaging and human health effects; demonstrate wide presence of 11 bisphenols in polystyrene take-out food containers from China, Canada, and Poland; report material quality influences BPA migration from polycarbonate cups; indicate higher BPA migration from lined cans than plastic packaging into meat based on probabilistic models; find bisphenols A, F, and S induce genotoxic effects and changes in human endogenous retroviruses (HERVs) expression using human blood cells
How to achieve a robust chemical testing program?
A commentary paper recommends strong engagement of the scientific community