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BPA and prostate cancer risk

CLARITY-BPA academic study confirms increased susceptibility to hormonally induced prostate cancer in rats developmentally exposed to bisphenol A

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Phthalates: impact on leiomyoma growth and mixture risk

Study identifies mono(2-ethyl-5-hydroxyhexyl) phthalate (MEHHP) exposure as high-risk factor for leiomyoma growth on epidemiological and mechanistic level; European biomonitoring of five reprotoxic phthalates demonstrates necessity to integrate mixture risk assessment into regulatory practice; targeted analysis shows migration of five phthalates from polypropylene food packaging

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Modeling chemicals in the human body

New strategy by EU Lab for Alternatives to Animal Testing focuses on computational models for chemical behavior in humans; supports steps to phase out animal testing

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FDA colloquium on in silico methods

Society of Toxicology and U.S. Food and Drug Administration host event on in silico testing methods; presentations focus on drivers for acceptance and treatment of uncertainties

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US EPA extends PV29 TSCA evaluation comment period

US Environmental Protection Agency (EPA) extends comment period for draft risk evaluation of C.I. Pigment Violet 29 (PV29) under its TSCA regulation; new draft adds previously confidential business data, solubility testing data, workplace air monitoring; concludes 11 of 14 conditions of use for PV29 pose unreasonable risk; toxicity debate ongoing also in Europe; EPA extends comment period for the revised draft until December 19, 2020