Scientists compile inventory list of chemicals used in printed paper and board FCMs; 1,769 single substances are non-evaluated for their toxicity; of these, 19 substances with actual use confirmed by FACET are included in ECHA’s lists for substances of concern
Aggregate exposure assessment for BPA
Scientists discuss aggregate exposure assessment for bisphenol A; source-to-dose (forward) and biomonitoring-based (backward) calculation resulted in similar estimates; 90% of exposure comes from diet and the remaining 10% mainly from dermal exposure
Petition calls for US FDA to consider cumulative effects
Coalition requests US Food and Drug Administration (FDA) to follow its own mandate to consider cumulative effects of chemicals present during safety assessments; covers chemicals directly added to food, substances migrating from food packaging, substances generally recognized as safe (GRAS); finds only 1 of 877 existing GRAS notifications adhered to requirement
Second study finds microplastics in human placenta
Clinical study investigates 10 microplastic types in human placenta and meconium; detects polyethylene, polypropylene, polystyrene, and polyurethane in the samples; highlights that evaluation and control of potential contamination is crucial
FDA accused of ‘willful ignorance’ regarding BPA
U.S. NGO Environmental Health News criticizes FDA’s approaches to designing and performing CLARITY-BPA study, interpreting its results; presents results of own investigation suggesting intentional manipulation, potential industry influence
Nanomaterials regulation in different countries
New JRC-study reviews regulatory measures for nanotechnology in food and feed production in different countries; only EU and Switzerland have legally binding nano-specific provisions
Evaluation framework for new approach methodologies
Multistakeholder study presents framework to evaluate new approach methodologies for assessing safety of chemicals; uses three steps and set of core principles, criteria to check if fit-for-purpose; provides case studies illustrating application
Focus on EDC controversy
Health & Environment article outlines debate around 2012 WHO/UNEP report on EDCs; discusses value of state-of-the-science reviews and need for systematic review methods in complex research problems
How to group PFAS? Expert panel finds no single answer
Panel of 12 experts in the fields of per- and polyfluoroalkyl substances (PFAS) chemistry and toxicology, general mixtures risk assessment and toxicokinetics participate in series of blind surveys; experts representing academia, regulators, and consultants; discuss how to group PFAS
DEHP disrupts insulin signaling
Scientists find that long-term oral exposure of adult rats to the phthalate DEHP disrupts insulin signaling pathways, resulting in the development of insulin resistance