National Institute of Environmental Health Sciences develops database with over 70 environmental health studies including economic analyses; new tool to help researchers consider costs of environmental exposures in studies
Study shows endocrine activity of BPA analogs
Bisphenol A alternatives detected in thermal paper in Switzerland, bisphenol F and bisphenol S shown to exhibit endocrine activity using in vitro and in silico tools, no significant endocrine activity found for the alternatives Pergafast® 201 and D-8
FPF Workshop 2019: Non-monotonicity explained
Ana Soto presents biological mechanisms underlying non-monotonic dose-responses, explains why non-monotonicity is ‘useful to organisms, challenging for regulators,’ discusses CLARITY-BPA’s successes and limitations
How to group PFAS? Expert panel finds no single answer
Panel of 12 experts in the fields of per- and polyfluoroalkyl substances (PFAS) chemistry and toxicology, general mixtures risk assessment and toxicokinetics participate in series of blind surveys; experts representing academia, regulators, and consultants; discuss how to group PFAS
DEHP disrupts insulin signaling
Scientists find that long-term oral exposure of adult rats to the phthalate DEHP disrupts insulin signaling pathways, resulting in the development of insulin resistance
Bisphenol S
Bisphenol S is used as a substitute of BPA in food contact materials, in a new context article the Food Packaging Forum reports on applications, toxicity, exposure and regulation of BPS
Consumer preference for glass packaging
Friends of Glass survey finds EU-consumers to favor glass packaging for food and drink; glass considered to be safest packaging material with lowest risk of interaction with food
Computational method outperforms animal tests
Predictions of acute health hazards by ‘data fusion’ read-across structure activity relationship (RASAR) modeling reported to be more reproducible than animal testing data
Plastics identified as source of legal liability
Minderoo Foundation finds liabilities from the health and environmental effects of microplastics and plastic-related chemicals to be worth more than $20 billion in the US by 2030; potentially up to $100 billion in liabilities expected by 2030 with the number expected to increase in the future; article published by the American Bar Association focuses on potential corporate liabilities from micro- and nanoplastics in particular
Standardizing Benchmark Dose (BMD) calculations
New study assesses reliability of standardized Benchmark Dose calculations, more dose groups and lower number of animals make for better BMD model