Emerging evidence and systematic analyses highlight adverse effects of bisphenols and phthalates on cardiovascular health; meta-analysis of US National Health and Nutrition Examination Survey data from 2003-2016 finds significant association of cardiovascular disease with bisphenol A; prenatal exposure particularly detrimental; calls for more mechanistic research, evaluation of cardiovascular safety profiles for substitution chemicals
Studies report on bisphenol exposure and health effects
Review summarizes plastic-associated bisphenol A (BPA) sources, exposure, and human health risks; dietary bisphenol exposure via packaged food consumption in Saudi Arabia is potential human health concern; review discusses bisphenols’ effects on the cardiovascular system and recommends human-relevant studies with bisphenols other than BPA; consensus scoring analysis identifies endocrine-disrupting food contact chemicals potentially interacting with nuclear receptors
PFAS research snapshot Q4 2023: presence, migration, health concerns, and regrettable substitution
Scientists detect two per- and polyfluoroalkyl substances (PFAS) in plastic food storage bags; study assesses PFAS in 119 single-use food packaging and tableware samples from around the world and detectes PFAS in 54%; two reviews raise awareness of PFAS impact on human liver health and safety issues connected with the PFAS substitutes – polyfluoroalkyl phosphate esters (PAPs); scientist calls for more research to assess combined environmental effect of microplastics and PFAS
Micro- and nanoplastics are released from different food contact articles
Researchers report cooking in non-stick Teflon cookware may lead to the release of thousands of micro- and nanoplastics; find 3 to 43 plastic particles prone to be released from Chinese polypropylene takeaway containers; detect around 1,500 microplastics/liter in Iranian bottled water; review points out that micro- and nanoplastic detection methods in food need validation and standardization
Microplastic effects on colon cells, blood lymphocytes, and gut-liver axis
Two in vitro studies analyze plastic particle effects using human cells; find polystyrene (PS) particles change metabolism of human colon cells similar to a carcinogen; PS nanoplastics may have cytotoxic and genotoxic potential on human blood lymphocytes; mouse study indicates microplastics increase risk of insulin resistance; researchers calculate particle ingestion from takeaway containers
Studies investigate extractable and leachable FCCs, present collision cross section database
Scientists develop collisions cross section (CCS) database for leachable and extractable food contact chemicals (FCCs) to help in chemical identification during targeted and untargeted analysis; database covers 1038 CCS values; study tentatively identifies >100 migrants from 24 plastic food packaging articles including 11 that are of potential concern or are priority hazardous substances
Projects launched to support GHS implementation in Africa
Kenya, Ghana, Cote d’Ivoire, Nigeria, and Rwanda implementing Globally Harmonized System of Classification and Labeling of Chemicals (GHS) in national policy; Sierra Leone and Malawi partner with the UN Environment Program (UNEP) to study chemical and waste management within the countries to design long term policies and projects
Plastics in a circular economy: research status, environmental leakage, food safety hazards
Recent studies perform semi-systematic review of published circular economy literature focusing on plastics over past 21 years, develop framework for plastics in circular economy; find Dutch food packaging plastic waste polluting oceans, question effectiveness of recycling; summarize chemical and microbial hazards related to circular food production systems
Bamboo in plastic FCMs not authorized in the EU
European Commission’s Working Group concludes that bamboo-based additives are not authorized per se for use in plastic food contact materials in the EU; business operators to explicitly demonstrate safety by migration testing; migration of melamine, formaldehyde of high concern; additional concerns about misleading labeling and advertising
Review discusses contaminants in canned food
Scientists summarize literature on chemicals in can-packaged food including metals, plastic-associated chemicals, and furans; report generally low contaminant levels but a lack of non-targeted and suspect screenings; find canning steps, internal and external factors to influence contaminant levels