Kate Guyton reviews the work of International Agency for Research on Cancer (IARC), underlines the essential role played by independent scientific experts, describes processes used for evidence synthesis and carcinogen classification; key characteristics of carcinogens constitute an important approach to cancer hazard identification
Chemicals in Plastic Packaging: Challenges for Regulation and the Circular Economy
Chronic PS nanoplastics exposure found to impact mitochondrial health, impairing cell metabolism
New study examines long-term effects of polystyrene (PS) nanoplastics on mitochondrial health under realistic exposure conditions; repeated exposure to PS nanoplastics impaired mitochondrial function and cell differentiation process, possibly linked to metabolic disorders, such as diabetes and obesity; other recent studies found that PS micro- and nanoplastics negatively affect immune function, pregnancy outcomes, and gut health in various models
Efforts to track plastic flows in EU and Canada
EU Joint Research Centre (JRC) publishes improved model of plastic product flows and recycling in the EU; new model design is easy to update when new information becomes publicly available; Canada consulting on a draft plastic products registry to track plastic flows in the country
Microplastics and human health: knowns and unknowns
Article published in Science lays out key knowledge gaps hindering human health risk assessments of microplastics, highlights lack of analytical tools to assess small microplastics and nanoplastics; estimated low exposure does not imply low risk
Surveys show public overwhelmingly in favor of measures against plastic pollution
Surveys by Greenpeace and World Wildlife Fund investigate public opinion on plastic reduction; 82% in favor of reducing plastic production; 90% support prohibition of harmful chemicals in plastic
Study reveals knowledge gaps on PET oligomers migrating from FCMs
Scientists investigate available research on hazard and exposure of 34 oligomers in PET for food contact; 74% of them found to migrate; only 38% have been tested for their safety using computer models, while only one was tested for safety in organisms; authors call for further research and better risk assessment
Regulatory challenges abound for hazardous chemicals in the EU
European Chemicals Agency (ECHA) report outlines four key challenge areas concerning chemicals regulation in the EU; discusses protection against most harmful chemicals, particularly those inducing neurotoxicity, immunotoxicity, endocrine disruption; underscores the need for data transparency and a “lack of comprehensive information on many substances”, particularly polymers
Update on recycled plastics FCM regulation in Europe
Standing Committee of the European Commission debates a slightly revised draft regulation on recycled plastics in food contact materials (FCMs); voting carried out as written procedure; final decision expected to be favorable
PFAS alternatives have incomplete hazard profiles, says OECD
Organization for Economic Co-operation and Development (OECD) reports replacements for long-chain PFAS in paper and board food packaging have little or no available hazard information; examines 58 long-chain PFAS replacements: 10 have been formally reviewed by governmental authorities, 26 by industry, 18 have no hazard assessments; Environmental Health News reports US states to consider over 200 PFAS bills in 2022