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Scientists explore the impact of long-term oral exposure of mammals to food packaging leachates on gut microbiome diversity, composition, and metabolites; report changes in gut microbiota and metabolites mainly associated with oxidative stress, immunity, and inflammatory responses
Researchers analyze plastic extracts for their chemical composition and promotion of obesity; find one-third induce fat production (adipogenesis); detect several thousand chemicals in the extracts, including known metabolism-disrupting chemicals
US Food and Drug Administration (FDA) maintains May 2022 decision to deny citizen petition asking the agency to ban eight ortho-phthalates in food contact
Scientific article evaluates mortality in relation to US adult phthalates exposure and quantifies costs; associates phthalate exposure with mortality stemming from all causes, cardiovascular mortality, and a societal cost of $39 to 47 billion per year
California expected to pass bill banning PFAS in food packaging; Michigan legislators reintroduce bill to ban PFAS, phthalates, and bisphenols in food packaging; Massachusetts’ Toxics Use Reduction Act program votes for expanding reporting requirements
European Food Safety Authority (EFSA) publishes final version of its opinion on risk to human health from per- and polyfluoroalkyl substances (PFAS) in food; sets group tolerable weekly intake limit of 4.4 ng/kg body weight for four most commonly measured PFAS in humans
Study of colon cancer cell lines finds polystyrene micro and nanoplastic particles (MNPs) can be absorbed into cancerous cells in experimental settings; the more aggressive cell line absorbed the most MNPs and presence of MNPs increased cell movement; evidence of persistence and bioaccumulation; authors argue MNPs fit criteria as substance of concern under REACH
Scientists assessed polyethylene terephthalate (PET) trays with different amounts of recycled content and produced by two different extrusion processes; find cyclic oligomer migration increases with recycled content amount, differs between the two processes; nontargeted screening identifies intentional and non-intentional substances, including marker compounds for recycled PET
Kate Guyton reviews the work of International Agency for Research on Cancer (IARC), underlines the essential role played by independent scientific experts, describes processes used for evidence synthesis and carcinogen classification; key characteristics of carcinogens constitute an important approach to cancer hazard identification
