Research article in The Journal of Clinical Endocrinology & Metabolism measures phthalates and other endocrine-disrupting chemicals (EDCs) in urine of 139 pregnant women, assesses occurrence of depression four months postpartum; finds detection of phthalates linked to low progesterone levels, association with depression
Migration of chemicals and microplastics from microwavable plastics
Scientists analyze migration of chemicals and microplastics from microwavable food containers; identify dozens of intentionally and non-intentionally added substances and up to over one million microplastics per liter in food simulants; migration partly exceeds Cramer class-based recommendations
Review clarifies essential-use concept and its application
Review resolves misinterpretations of the essential-use concept and exemplifies the concept’s application using case studies, e.g., on per- and polyfluoroalkyl substances (PFAS); classifies concept as feasible and a novel, effective, and more rapid approach of managing chemicals of potential concern
Review discusses contaminants in canned food
Scientists summarize literature on chemicals in can-packaged food including metals, plastic-associated chemicals, and furans; report generally low contaminant levels but a lack of non-targeted and suspect screenings; find canning steps, internal and external factors to influence contaminant levels
Thailand proposes draft regulation for paper FCMs
Thailand publishes draft regulation for chemicals in paper food contact materials (FCMs), affects non-colored paper and board containers; limits concentrations of heavy metals, phthalates, bisphenol A and benzophenone; draft open for consultation until May 11, 2021
Studying phthalates: Linkage with dietary habits and molecular changes
Biomonitoring finds regular takeaway food consumption increases phthalate exposure; intervention study links plastic packaged hot soup consumption with increased phthalate exposure and changes in mRNA expression of inflammatory cytokines; structural analysis suggests non-phthalate alternative plasticizers have potential for thyroid hormone disruption
Colombia issues resolution on glass and ceramic FCMs
Technical regulation sets specific migration limits for lead and cadmium from glass and ceramic food contact materials (FCMs); provides guides on which products are within scope, limits vary with article type and size
GUTS model adapted to chemical mixtures
Study in Environmental Science Technology on adapted General Unified Threshold model for Survival (GUTS) for environmental risk assessment of chemical mixtures; includes time dimension, approach can be extended to multiple compounds, evaluate synergistic or additive interaction
Call to consider persistence as CLP hazard class
Global PFAS Science Council comments on proposed revision of European Union classification, labeling and packaging (CLP) regulation; calls for the CLP to “introduce persistence as a stand-alone hazard classification”
French order on food contact rubber
France publishes new Order on food contact rubber and pacifiers for infants and toddlers; updates lists of authorized substances, their specifications, restrictions; law enters into force on July 1, 2021