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Perspective: From "forever chemicals" to fluorine-free alternatives

Perspective article in Science argues PFAS substitution is urgently needed due to their persistence, hazards, and recent regulatory actions; avoiding “regrettable substitution” and finding suitable replacements requires a strategic approach; PFAS replacements should have an effective functionality, minimal safety issues, and a minimal environmental footprint; open data sharing can accelerate the discovery, development, and implementation of safer alternatives

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ASEAN member actions on plastic and chemical pollution

Nations in Southeast Asia collectively working on reducing plastic pollution and related chemical hazards; Association of Southeast Asian Nations (ASEAN) signs off on project to “combat” marine plastic; Thailand plans ban on plastic scrap imports; new research available on sources of plastic pollution in Indonesia and Vietnam; Vietnam and Singapore implementing stricter chemical regulations; extended producer responsibility for plastic waste becomes law in Philippines

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Chronic PS nanoplastics exposure found to impact mitochondrial health, impairing cell metabolism

New study examines long-term effects of polystyrene (PS) nanoplastics on mitochondrial health under realistic exposure conditions; repeated exposure to PS nanoplastics impaired mitochondrial function and cell differentiation process, possibly linked to metabolic disorders, such as diabetes and obesity; other recent studies found that PS micro- and nanoplastics negatively affect immune function, pregnancy outcomes, and gut health in various models

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ECHA publishes five-year REACH and CLP review

European Chemicals Agency (ECHA) publishes five-year review on the operation of REACH and CLP regulations; discusses impacts and shortcomings; 71 chemicals added to harmonized classification and labeling list; in 90% of cases, chemical’s general safety assessment is performed and communicated down the supply chain but half are incomplete; 33% of safety data sheets for mixtures not compliant, 17% incorrectly classified; 44% of chemicals needing authorization due to health risks are being phased out likely due to REACH