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EFSA: Draft opinion on NMDR open for consultation

European Food Safety Authority’s (EFSA) draft opinion reviews literature on assessment of non-monotonic dose responses (NMDRs), finds lack of standards for statistical approaches; suggests stepwise approach for ambiguous ‘apparent’ NMDRs; approach applied in two case studies finds no NMDR for bisphenol A (BPA) but does for di(2-ethylhexyl)phthalate (DEHP); open for comments until February 4, 2021

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Benchmarking in vitro toxicity of plastics

Scientists investigate in vitro toxicity and chemical composition of plastic consumer products made of different polymers; high baseline toxicity of polylactic acid (PLA) bioplastics; food contact status does not necessarily imply lower toxicity