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Microplastics impacts on the reproductive system and offspring

Scientists report human-relevant polystyrene (PS) microplastic concentrations change mice placental metabolism; show nanoplastics have variable effects on placental enzymes using simulations; find pre- and postnatal PS microplastic exposure affects male mice testis development and fertility; recommend future research to analyze multigenerational effects

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Phthalates: impact on leiomyoma growth and mixture risk

Study identifies mono(2-ethyl-5-hydroxyhexyl) phthalate (MEHHP) exposure as high-risk factor for leiomyoma growth on epidemiological and mechanistic level; European biomonitoring of five reprotoxic phthalates demonstrates necessity to integrate mixture risk assessment into regulatory practice; targeted analysis shows migration of five phthalates from polypropylene food packaging

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Microplastics may affect the human microbiome

Scientists explore potential impacts of microplastics on human intestine ecology; microplastics may drive unhealthy changes in the gut microbiome; authors highlight importance of assessing human microplastics exposure and hazards for the gut