Small pilot study analyzes saphenous vein tissues from five individuals and detects 15 plastic particles/g tissue indicating transport of plastic particles within human tissue; review concludes more research needed to elucidate the potential carcinogenicity of micro- and nanoplastics; researchers find potential connection between colorectal cancer and microplastic exposure level; preliminary study report microplastic presence in four out of six urine samples 15 plastic particles/g of tissue
NORMAN-SLE – Open and FAIR suspect screening
Scientists publish creation and implementation details of The NORMAN Suspect List Exchange (NORMAN‑SLE); now openly available as a FAIR (Findable, Accessible, Interoperable, Reusable) chemical information resource; includes 99 suspect lists and 100,000 substances; new submissions are welcome
UN report highlights impact of plastics on human rights
UN Special Rapporteur on toxics and human rights issues report on the stages of the plastics cycle and their impacts on human rights; calls “the whole cycle of plastics… a global threat to human rights”
German BfR comments on the Chemicals Strategy for Sustainability
The German Federal Institute for Risk Assessment (BfR) comments on the EU’s Chemicals Strategy for Sustainability (CSS); criticizes the alleged exclusion of scientific risk assessment experts in the development and implementation of the CSS; comments supported by others with demonstrated ties to chemical industry.
BPA disrupts human egg maturation
New study investigates effect of BPA exposure on human egg development and infers link to infertility
Free BPA detected in human serum samples
U.S. round robin study looks into contamination sources of BPA in human biomonitoring studies
Researchers detect microplastics in human semen and heart
Four recent studies assess microplastics: in human semen, heart, from baby food containers, and suitability of in vitro models to investigate human health effects; find microplastics in six out of ten semen samples, find impacts on semen quality; samples from cardiac surgery patients contain microplastics in heart and surrounding tissue; billions of nano- and microplastics released from plastic baby food containers; outline challenges and recommendation of studying plastic particles in vitro
Microplastic effects on colon cells, blood lymphocytes, and gut-liver axis
Two in vitro studies analyze plastic particle effects using human cells; find polystyrene (PS) particles change metabolism of human colon cells similar to a carcinogen; PS nanoplastics may have cytotoxic and genotoxic potential on human blood lymphocytes; mouse study indicates microplastics increase risk of insulin resistance; researchers calculate particle ingestion from takeaway containers
Phthalates: 'Safe' levels may not be protective of human health
New peer-reviewed scientific study by the Food Packaging Forum and academic scientists shows regulatory ‘safe’ limits for human exposure to phthalates may be set at levels not sufficiently protective of human health; analysis reviews 38 human health studies; highlights need for revising current approach and to re-assess the safety of chemicals already on the market
Unexpected SVHC phthalate metabolite found in humans, including children
German biomonitoring study finds mono-n-hexyl phthalate in majority of samples, indicating widespread exposure to substance of very high concern (SVHC) di-n-hexyl phthalate or related compounds; sources of exposure currently under investigation; contribution of food contact materials to human exposure possible, but only limited data available