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BPA causes abnormal breast growth in mice
Study connects prenatal low dose exposure to BPA with abnormal breast growth in mice
Stakeholders prepare for the second Plastics Treaty negotiation
United Nations Environment Program (UNEP), industry organizations, scientific research groups, and civil society organizations publish flurry of reports and policy briefs in preparation for second meeting of the Intergovernmental Negotiating Committee on Plastic Pollution (INC-2); meeting takes place in Paris, France May 29 – June 2, 2023
Liver tumors in BPA exposed mice
New study finds liver tumors in BPA exposed mice, first to detect tumors rather than precancerous lesions
BPA can alter parenting behavior in mice
A new study finds that early exposure to BPA reduces parental care in mice
Scientific studies evaluate microplastic effects on human cells
Rapid review assesses microplastics impacts on human cells and reports thresholds of effects lower than previously predicted; scientific study finds polystyrene (PS) microplastics to have nephrotoxic potential; reproduction and fertility study with mice reports PS microplastics to affect females more than males
BPA causes metabolic changes at low, but not at high dose
New study investigates effects of prenatal BPA exposure on metabolism in vivo
First proposals put forward for global treaty to end plastic pollution
Countries are submitting proposals to the UN Environment Program to guide Plastics Treaty development; US proposes treaty focus on downstream effects – reuse and recycling; proposal from 40-nation ‘high ambition coalition’ proposes setting up limits on polymer production, eliminating certain polymers and products; over 60 proposals received so far; stakeholder registration is open for the next negotiating meeting for the Plastics Treaty in Paris, France in May 2023
Microplastics impacts on the reproductive system and offspring
Scientists report human-relevant polystyrene (PS) microplastic concentrations change mice placental metabolism; show nanoplastics have variable effects on placental enzymes using simulations; find pre- and postnatal PS microplastic exposure affects male mice testis development and fertility; recommend future research to analyze multigenerational effects
Scientists explore effects of micro- and nanoplastics on mammals, including humans
Research studies show maternal polystyrene (PS) particle exposure can cause testicular and hepatic toxicity in male mouse offspring; report PS microplastics affect rat ovary function; find correlation between human fecal microplastics levels and Inflammatory Bowel Disease; reviews summarize potential human health effects; study develops a tool to screen and prioritize micro-and nanoplastics toxicity studies for human health risks evaluation