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Scientists review molecular mechanisms underlying low-dose actions of estrogenic EDCs, focusing on extranuclear signaling; BPA effects in pancreas and heart mediated through alpha, beta, and membrane-associated forms of estrogen receptor
Two studies investigate microplastic presence or effects in female and male reproductive organs; small cohort study finds low number of microplastics to be present in human amniotic fluid besides the placenta; in vitro and mice in vivo study reports microplastics induce premature testicular aging and identifies underlying pathways
New EFSA scientific study tests different mixtures of mineral oil saturated hydrocarbons (MOSH), relevant to human diet, in rats; bioaccumulation at low dose MOSH exposure in humans possibly underestimated; MOSH appear persistent in adipose tissue
Scientists integrate and interpret data from 8 of the 14 academic studies completed under the CLARITY-BPA project; link bisphenol A (BPA) exposure to impacts across multiple organs including brain, heart, prostate, mammary gland, ovaries; strengthen confidence in low-dose effects of BPA; co-authors to present results in webinar on July 21, 2020
Study provides an in-depth look at microplastics in the male reproductive system, analyzes human and mouse samples to chart concentrations and polymer types; finds microplastics in all human testes samples and majority of semen samples; larger plastic particles may get trapped in testis, leading to higher concentrations; identifies correlation between urbanization, home-cooked meals, and body scrub used to microplastics concentration
Series of new studies finds mixtures of everyday non-carcinogenic chemicals to be of concern for causing cancer; individual chemicals present at low levels; opportunity for improvement of chemical risk assessment and primary prevention of cancer
Scientists report most large companies commit to reducing plastic pollution but focus on recycling; extrusion of recycled materials and legacy compounds in recycled materials as safety challenge; some substances increase others decrease with the increase in recycled content in polyethylene terephthalate (PET) bottles; tentatively identify 212 volatile chemicals in 57 different recycled PET flakes available in China; present migration model to characterize the exposure and risk of PET oligomers
At the One Ocean Summit on February 10, the United States and France delivered a joint statement supporting a global plastics treaty; agree treaty should address whole lifecycle of plastics and include binding commitments
New study investigates metabolic effects of DEHP exposure in mice in vivo and in vitro; increased weight gain and fat mass, impaired insulin tolerance and changes in serum metabolites observed
Friends of Europe hosts online debate bringing together stakeholder groups from industry, regulatory agencies, and NGOs; considers how to achieve a circular plastics economy, discusses the necessity of a global plastic treaty, prevention of plastic waste trade and illegal waste dumping, extended producer responsibility schemes (EPRs), need for unified EU plastic waste market; discussions build on report by European Environment Agency, case study by Zero Waste Europe and report by Ellen MacArthur Foundation
