Review article by EU Commission’s Joint Research Centre and collaborators discusses development and use of computational prediction models for regulatory toxicology and how it can be supported by the Adverse Outcome Pathways framework
Sustainability in Focus: From Environmentally-friendly Packaging to Responsible Ingredients Sourcing
Chemicals of concern in paper and board food packaging
Danish consumer council finds fluorocarbons and mineral oils in paper and board packaging in direct contact with food
EFSA considers co-monomer as safe for food contact
EFSA publishes scientific opinion on 1,4:3,6-dianhydrosorbitol
EC publishes BPA roadmap
DG SANTE releases roadmap on new measures on BPA in FCMs; different options from no policy change to EU-wide ban on BPA in FCMs discussed and assessed
EFSA assesses monomer for polycarbonate FCMs
EFSA’s CEF Panel considers dimethyl carbonate safe for making polycarbonate repeated-use food contact articles, under certain conditions
MERCOSUR publishes draft silicone FCM regulation
South American trade bloc MERCOSUR is updating its standards for silicone food contact materials; includes positive lists and specific migration limits for metal salts; stakeholders can comment on the draft until May 12, 2023; Argentina and Uruguay have already notified the World Trade Organization of impending changes
DEHP and male reproductive health
New research finds reproductive abnormalities in male mice prenatally exposed to DEHP and their succeeding generations; 3rd generation effects most pronounced at lowest exposure dose
Scientists detect microplastics in amniotic fluid, effects on testicular aging
Two studies investigate microplastic presence or effects in female and male reproductive organs; small cohort study finds low number of microplastics to be present in human amniotic fluid besides the placenta; in vitro and mice in vivo study reports microplastics induce premature testicular aging and identifies underlying pathways
Neurological effects caused by melamine
High doses of melamine during pregnancy affect male offspring